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PZ0343

Sigma-Aldrich

PF-06260414

≥98% (HPLC)

Synonym(s):

6-[(4R)-tetrahydro-4-methyl-1,1-dioxido-2H-1,2,6-thiadiazin-2-yl]-1-isoquinolinecarbonitrile

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About This Item

Empirical Formula (Hill Notation):
C14H14N4O2S
CAS Number:
1612755-71-1
Molecular Weight:
302.35
UNSPSC Code:
12352200
PubChem Substance ID:
329823852
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

light orange to dark orange

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

room temp

SMILES string

C[C@H](CNS1(=O)=O)CN1C2=CC3=CC=NC(C#N)=C3C=C2

InChI

1S/C14H14N4O2S/c1-10-8-17-21(19,20)18(9-10)12-2-3-13-11(6-12)4-5-16-14(13)7-15/h2-6,10,17H,8-9H2,1H3/t10-/m1/s1

InChI key

ZKAVFOXYJCREBQ-SNVBAGLBSA-N

Biochem/physiol Actions

PF-06260414 is a nonsteriodal selective androgen receptor modulator (SARM). PF-06260414 is being investigated as a treatment for muscle weakening such as that associated with muscular dystrophy and the sarcopenia associated with natural aging. PF-06260414 has anabolic activity without unwanted androgenic activity on reproductive organs, liver or kidneys.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000309563
0000309563
0000144628
0000144652

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Emiliano Ventura et al.
Journal of chromatography. A, 1600, 183-196 (2019-05-06)
A semi-quantitative method was developed to monitor the misuse of 15 SARM compounds belonging to nine different families, in urine matrices from a range of species (equine, canine, human, bovine and murine). SARM residues were extracted from urine (200 μL) with

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