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I1252

Sigma-Aldrich

DL-Isocitric acid trisodium salt hydrate

≥93%

Synonym(s):

threo-DsLs-Isocitric acid trisodium salt hydrate

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About This Item

Empirical Formula (Hill Notation):
C6H5Na3O7 · xH2O
CAS Number:
Molecular Weight:
258.07 (anhydrous basis)
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.25

Assay

≥93%

SMILES string

O.[Na+].[Na+].[Na+].OC(C(CC([O-])=O)C([O-])=O)C([O-])=O

InChI

1S/C6H8O7.3Na.H2O/c7-3(8)1-2(5(10)11)4(9)6(12)13;;;;/h2,4,9H,1H2,(H,7,8)(H,10,11)(H,12,13);;;;1H2/q;3*+1;/p-3

InChI key

BPEHKAXIRZOKIS-UHFFFAOYSA-K

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ming-dong Wang et al.
Chinese medical journal, 124(17), 2611-2615 (2011-11-02)
Site A132Arg mutations potentially impair the affinity of isocitrate dehydrogenase 1 (IDH1) for its substrate isocitrate (ICT), consequently reducing the production of α-ketoglutarate and leading to tumor growth through the induction of the hypoxia-inducible factor-1 (HIF-1) pathway. However, given that
Ho-Ju Fan-Chiang et al.
Journal of AOAC International, 93(3), 956-965 (2010-07-16)
Sugar and nonvolatile acid analyses were conducted on 52 samples of blackberries (Rubus spp), the objective being to develop a compositional database for evaluating authenticity and quality. Brix ranged from 6.88 to 16.83, with a mean of 10.82. Titratable acidity
An-Ping Lin et al.
Biochemistry, 50(38), 8241-8250 (2011-08-25)
Yeast NAD(+)-specific isocitrate dehydrogenase is an allosterically regulated octameric enzyme composed of four heterodimers of a catalytic IDH2 subunit and a regulatory IDH1 subunit. Despite structural predictions that the enzyme would contain eight isocitrate binding sites, four NAD(+) binding sites
Anita Rywińska et al.
Preparative biochemistry & biotechnology, 42(3), 279-291 (2012-04-19)
The effects of agitation rates from 400 to 900 rpm and aeration rates ranging from 0.18 to 0.6 vvm on biomass and citric acid production on glycerol media by acetate-negative mutants of Yarrowia lipolytica, Wratislavia 1.31 and Wratislavia AWG7, in
Weihua Gao et al.
Mikrobiologiia, 79(6), 774-778 (2011-03-31)
Bacillus subtilis aconitase, encoded by the citB gene, is a bifunctional enzyme, which can not only interconvert citrate and isocitrate, but also has the RNA binding function similar to the eukaryotic protein IRP-1 (iron regulatory protein 1). Homology analysis between

Protocols

We describe here a rapid and sensitive method to separate and measure D-2-OHG and L-2-OHG enantiomers using high-resolution mass spectrometry (HRMS) detection.

Chromatograms

application for HPLC

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