This product is soluble in water at 50 mg/ml.
D3447
Doxycycline hydrochloride
Synonym(s):
2-Naphthacenecarboxamide, 4-(dimethylamino)- 1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aR,5S,5aR,6R,12aS)-
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About This Item
Empirical Formula (Hill Notation):
C22H24N2O8 · HCl
CAS Number:
Molecular Weight:
480.90
MDL number:
UNSPSC Code:
51284028
NACRES:
NA.85
Pricing and availability is not currently available.
Recommended Products
biological source
synthetic
Quality Level
form
powder
color
yellow
antibiotic activity spectrum
Gram-negative bacteria
Gram-positive bacteria
mycoplasma
parasites
Mode of action
protein synthesis | interferes
storage temp.
−20°C
InChI
1S/C22H24N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25-27,31-32H,23H2,1-3H3;1H/b21-13-;/t7-,10+,14+,15-,17-,22-;/m0./s1
InChI key
VLUQVUWDECWBTL-UQVCFKGQSA-N
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General description
Doxycycline is a member of the tetracycline antibiotics group, and is commonly used to treat a variety of infections. It is a Broad spectrum antibiotic and bacteriostatic. Doxycycline shows antiprotozoal properties and is a potent inhibitor of MMPs (matrix metalloproteinases) in vivo.
Application
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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IS DOXYCYCLINE HYDROCHLORIDE (D3447) SOLUBLE IN WATER 50 MG/ML?
1 answer-
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What is the best way to solubilize the product for cell culture and animal use?
1 answer-
This product has not been tested for use in cell culture. However, product D5207 is a cell culture tested Doxycycline Hyclate. The Hyclate and the Hydrochloride salt forms are soluble in water at roughly equal rates. For dosing purposes, the unique molecular weight of each must be considered. Please see the link below to the product data sheet for the cell culture version of this product. This information offered in this document may be applied to the D3447:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/402/297/d5207dat.pdfNote that neither of these products are sterile. Prepared stock solutions must be filter sterilized prior to adding them to the culture medium.
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