D201863

1,4-Dioxane

ReagentPlus^®, ≥99%, contains ≤25 ppm BHT as stabilizer

• Synonym(s): Diethylene oxide, Dioxane
• Empirical Formula (Hill Notation): C₄H₈O₂
• CAS Number: 123-91-1
• Molecular Weight: 88.11
• Beilstein: 102551
• EC Number: 204-661-8
• MDL number: MFCD00006571
• UNSPSC Code: 12352005
• PubChem Substance ID: 329798726
• NACRES: NA.21
• Assay: ≥99%
• technique(s): thin layer chromatography (TLC): suitable
• bp: 100-102 °C (lit.)
• vapor pressure: 27 mmHg ( 20 °C); 40 mmHg ( 25 °C)

Properties

• vapor density: 3 (vs air)
• Quality Level: 100
• vapor pressure: 27 mmHg ( 20 °C); 40 mmHg ( 25 °C)
• product line: ReagentPlus^®
• Assay: ≥99%
• form: liquid
• autoignition temp.: 356 °F
• contains: ≤25 ppm BHT as stabilizer
• expl. lim.: 22 %
• technique(s): thin layer chromatography (TLC): suitable
• refractive index: n20/D 1.422 (lit.)
• pH: 6.0-8 (20 °C, 500 g/L)
• bp: 100-102 °C (lit.)
• mp: 10-12 °C (lit.)
• density: 1.034 g/mL at 25 °C (lit.)
• SMILES string: C1COCCO1
• InChI: 1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2
• InChI key: RYHBNJHYFVUHQT-UHFFFAOYSA-N

Description

Application

1,4-Dioxane can be used as a solvent:

• To synthesize 1,3-diamines and amino alcohols via 2-azaallyl anion benzylic ring-opening of aziridines.
• In the RAFT polymerization of acryclic acid[1].
• In the synthesis of cross-linked triblock copolymer hydrogels[2].

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H319,H335,H350
• Precautionary Statements: P202 - P210 - P233 - P240 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH019,EUH066
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 51.8 °F - closed cup
• Flash Point(C): 11 °C - closed cup