522554

2-Hydroxyphenylboronic acid pinacol ester

98%

• Synonym(s): 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
• Empirical Formula (Hill Notation): C₁₂H₁₇BO₃
• CAS Number: 269409-97-4
• Molecular Weight: 220.07
• MDL number: MFCD02093754
• UNSPSC Code: 12352103
• PubChem Substance ID: 24874280
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• refractive index: n20/D 1.506 (lit.)
• bp: 282 °C (lit.)
• density: 1.05 g/mL at 25 °C (lit.)
• SMILES string: CC1(C)OB(OC1(C)C)c2ccccc2O
• InChI: 1S/C12H17BO3/c1-11(2)12(3,4)16-13(15-11)9-7-5-6-8-10(9)14/h5-8,14H,1-4H3
• InChI key: VLROJECCXBBKPZ-UHFFFAOYSA-N

Description

Application

Reactant involved in:

• Synthesis of indolo-fused heterocyclic inhibitors of polymerase enzyme of hepatitis C
• Studies of pi-interactions, electronic structure and transient UV absorption of subphthalocyanine-borate-bridged ferrocene-fullerene conjugates
• Synthesis of subphthalocyanine and fused-ring nicotine derivatives
• Suzuki-Miyaura coupling-triflation sequence, reduction and salt formation for synthesis of hydroxylated oligoarene phosphines

Widely used in Suzuki coupling chemistry.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335
• Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable