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Sigma-Aldrich

Fmoc-Met-OH

≥98.0% (HPLC), for peptide synthesis

Synonym(s):

Fmoc-L-methionine

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About This Item

Empirical Formula (Hill Notation):
C20H21NO4S
CAS Number:
Molecular Weight:
371.45
Beilstein:
4300266
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

Fmoc-Met-OH, ≥98.0% (HPLC)

Quality Level

Assay

≥98.0% (HPLC)

optical activity

[α]20/D -29.5±1.5°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

mp

121-123 °C (lit.)

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

CSCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C20H21NO4S/c1-26-11-10-18(19(22)23)21-20(24)25-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/t18-/m0/s1

InChI key

BUBGAUHBELNDEW-SFHVURJKSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Carolyn C Woodroofe et al.
Chembiochem : a European journal of chemical biology, 21(4), 508-516 (2019-08-01)
The reversible oxidation of methionine residues in proteins has emerged as a biologically important post-translational modification. However, detection and quantitation of methionine sulfoxide in proteins is difficult. Our aim is to develop a method for specifically derivatizing methionine sulfoxide residues.
Dennis Kubiczek et al.
Macromolecular bioscience, 20(4), e2000005-e2000005 (2020-02-28)
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Marcus Pickhardt et al.
Current Alzheimer research, 14(7), 742-752 (2017-02-06)
Anti-aggregation drugs play an important role in therapeutic approaches for Alzheimer's disease. We have previously developed a number of compounds that are able to inhibit the pathological aggregation of Tau protein. One common obstacle to application is the limited penetration
Gizella Csire et al.
Journal of inorganic biochemistry, 170, 195-201 (2017-03-07)
The prion protein (PrP) is a membrane-anchored cell surface glycoprotein containing 231 amino acids. It has been associated with a group of neurodegenerative disorders. Copper(II) interaction with the Human Prion 103-112 fragment and its mutants has been studied with various
Stefan Eissler et al.
Journal of peptide science : an official publication of the European Peptide Society, 23(10), 757-762 (2017-06-22)
In solid-phase peptide synthesis, the nominal batch size is calculated using the starting resin substitution and the mass of the starting resin. The starting resin substitution constitutes the basis for the calculation of a whole set of important process parameters

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