Removal of GenX by APTES functionalized diepoxyoctane cross-linked chitosan beads: Cross-linked and aminated chitosan beads were synthesized using 1,2:7,8-diepoxyoctane and 3-aminopropyl triethoxysilane. These beads were studied for their efficiency in removing GenX, a problematic environmental pollutant, demonstrating a potential application in water treatment technologies (M Vakili, F Gholami, HM Zwain, W Wang… - Journal of …, 2023 - Elsevier).
The Biochemical journal, 251(3), 935-938 (1988-05-01)
A new method for the chemical labelling of nucleic acid with biotin to produce non-radioactive probes has been developed. NN'-Bis-(3-aminopropyl)butane-1,4-diamine (spermine) and long-chain diamino compounds (diaminohexane, diaminodecane and diaminododecane) were linked covalently to biotin and the resultant conjugates were attached
Journal of biomaterials science. Polymer edition, 17(4), 419-433 (2006-06-14)
Hyaluronic acid (hyaluronan, HA) has many medical applications as a biomaterial. To enhance its biostability, a novel hydrogel of cross-linked hyaluronic acid was prepared using a double cross-linking process, which involves building cross-linkages between hydroxyl group pairs and carboxyl group
The time-dependent dose-response relationships for the induction of DNA double-strand breaks (DSB) assessed by pulsed-field gel electrophoresis (PFGE) and for viability (evaluated by the MTT cytotoxicity test) were investigated in order to discriminate between genotoxic and cytotoxic mechanisms of DNA
Chemical research in toxicology, 9(6), 994-1000 (1996-09-01)
The carcinogenicity of epoxide compounds has been attributed to covalent binding to DNA. Whereas monoepoxides form only monoadducts, diepoxides can form both monoadducts and interstrand cross-links. The latter are believed to be the more significant cytotoxic lesions as diepoxides are
Molecular and cellular biology, 5(1), 1-6 (1985-01-01)
The mutation e1662 is an allele of the Caenorhabditis elegans unc-54 gene induced with the difunctional alkylating agent 1,2,7,8-diepoxyoctane. unc-54 encodes the major myosin heavy chain isozyme of body wall muscle cells. Filter-transfer hybridization and DNA sequence analysis show that
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
