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Merck

Total synthesis of aspercyclides A and B via intramolecular oxidative diaryl ether formation.

Organic letters (2012-08-09)
Tatsuya Yoshino, Itaru Sato, Masahiro Hirama
RÉSUMÉ

A highly efficient total synthesis of the 11-membered cyclic aspercyclides A (1) and B (2) has been achieved by chemo- and regioselective intramolecular oxidative C-O bond formation from differently substituted diphenols.

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