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1544508

USP

Piroxicam

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

4-Hydroxy-2-methyl-3-(pyrid-2-yl-carbamoyl)-2H-1,2-benzothiazine 1,1-dioxide

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About This Item

Formule empirique (notation de Hill):
C15H13N3O4S
Numéro CAS:
36322-90-4
Poids moléculaire :
331.35
Numéro MDL:
MFCD00057317
Code UNSPSC :
41116107
ID de substance PubChem :
329750878
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

piroxicam

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

CN1C(C(=O)Nc2ccccn2)=C(O)c3ccccc3S1(=O)=O

InChI

1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)

Clé InChI

QYSPLQLAKJAUJT-UHFFFAOYSA-N

Informations sur le gène

human ... PTGS1(5742) , PTGS2(5743)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Piroxicam USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Piroxicam Capsules
  • Piroxicam Compounded Cream
  • Piroxicam Compounded Oral Suspension

Actions biochimiques/physiologiques

Cyclooxygenase inhibitor.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

P2130000

Piroxicam, European Pharmacopoeia (EP) Reference Standard

Y0001475

Piroxicam for system suitability, European Pharmacopoeia (EP) Reference Standard

BP463

Piroxicam, British Pharmacopoeia (BP) Reference Standard

1544541

Piroxicam Related Compound D, United States Pharmacopeia (USP) Reference Standard

1544574

Piroxicam Related Compound G, United States Pharmacopeia (USP) Reference Standard

1544600

Piroxicam Related Compound J, United States Pharmacopeia (USP) Reference Standard

1544520

Piroxicam Related Compound B, United States Pharmacopeia (USP) Reference Standard

1544519

2-Aminopyridine, United States Pharmacopeia (USP) Reference Standard

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Mentions de danger

H301,H373

Classification des risques

Acute Tox. 3 Oral - STOT RE 2 Oral

Organes cibles

Gastrointestinal tract

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Therapeutic focus. Piroxicam.
A Calin
The British journal of clinical practice, 42(4), 161-164 (1988-04-01)
D L Earnest et al.
Journal of cellular biochemistry. Supplement, 16I, 156-166 (1992-01-01)
Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) widely used for treatment of inflammatory arthritis. Recent experimental and clinical studies suggest that piroxicam, as well as other NSAIDs, may be useful for chemoprevention of colon cancer. While there is less information
J Y Reginster et al.
European journal of rheumatology and inflammation, 12(4), 38-46 (1993-01-01)
Analgesics continue to be the mainstay of therapy in osteoarthritis. Non-steroidal anti-inflammatory drugs (NSAIDs) play an important role, particularly where there is a significant inflammatory component to the osteoarthritis. Piroxicam-beta-cyclodextrin (PBC) is a new formulation in which piroxicam has been
C Scarpignato
Current medicinal chemistry, 20(19), 2415-2437 (2013-02-12)
Although NSAIDs are very effective drugs, their use is associated with a broad spectrum of adverse reactions in the liver, kidney, cardiovascular (CV) system, skin and gut. Gastrointestinal (GI) side effects are the most common and constitute a wide clinical
Kusum Rathore et al.
Translational research : the journal of laboratory and clinical medicine, 164(2), 158-168 (2014-03-19)
Development and characterization of animal models for human cancers is important for the improvement of diagnosis and therapy. The oral squamous cell carcinoma (OSCC) of domestic animals resembles human OSCC in many aspects; thus, cell lines derived from OSCC of
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