1514008

Phenacetin Melting Point Standard

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : Phenacetin, 1-Acetyl-p-phenetidin, 4′-Ethoxyacetanilide, N-(4-Ethoxyphenyl)acetamide, p-Acetophenetidide, Acetophenetidin
• Formule linéaire : CH₃CONHC₆H₄OC₂H₅
• Numéro CAS: 62-44-2
• Poids moléculaire : 179.22
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329750741
• EC Number: 200-533-0
• Beilstein/REAXYS Number: 1869238
• MDL number: MFCD00009094

Propriétés

• grade: pharmaceutical primary standard
• agency: USP
• API family: phenacetin
• manufacturer/tradename: USP
• mp: 133-136 °C
• application(s): pharmaceutical; pharmaceutical (small molecule)
• format: neat
• SMILES string: CCOc1ccc(NC(C)=O)cc1
• InChI: 1S/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,11,12)
• InChI key: CPJSUEIXXCENMM-UHFFFAOYSA-N

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Phenacetin Melting Point Standard (Phenacetin) is a lipid-soluble drug with moderate solubility with aqueous solvents. Its oral absorption is based on formulation factors like particle size. Its major metabolic route is O-dealkylation to paracetamol and its minor pathways are deacetylation and hydroxylation to form pphenetidine, 2-hydroxyphenetidine, 2- and 3-hydroxyphenacetin and N-hydroxyphenacetin.

Application

Phenacetin Melting Point Standard USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Substrate of CYP1A2 and CYP2D6.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informations sur la sécurité

• Mot-clé: Danger
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Pictogrammes: GHS08,GHS07
• Codes de danger: H302,H317,H341,H350
• Mentions de précaution: P202 - P261 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1A - Muta. 2 - Skin Sens. 1
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects