1365065

Levothyroxine sodium hydrate

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : 3,3′,5,5′-Tetraiodo-L-thyronine monosodium salt hydrate, Sodium O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine hydrate
• Formule empirique (notation de Hill) : C₁₅H₁₀I₄NNaO₄ · xH₂O
• Numéro CAS: 25416-65-3
• Poids moléculaire : 798.85 (anhydrous basis)
• NACRES: NA.24
• PubChem Substance ID: 329750053
• UNSPSC Code: 41116107
• MDL number: MFCD06408007

Propriétés

• grade: pharmaceutical primary standard
• agency: USP
• API family: levothyroxine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O
• InChI: 1S/C15H11I4NO4.Na.H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;1H2/q;+1;/p-1/t12-;;/m0../s1
• InChI key: ANMYAHDLKVNJJO-LTCKWSDVSA-M
• Gene Information: human ... THRA(7067), THRB(7068)

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Levothyroxine sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informations sur la sécurité

• pictograms: GHS08
• signalword: Danger
• hcodes: H372
• pcodes: P260 - P264 - P270 - P314 - P501
• Hazard Classifications: STOT RE 1
• target_organs: Thyroid,Cardio-vascular system,Kidney
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable