1012780

Alendronate sodium

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : Alendronate sodium trihydrate, 4-amino-1-hydroxy-1-phosphonobutyl phosphonic acid, monosodium, MK-217
• Formule empirique (notation de Hill) : C₄H₁₂NaNO₇P₂ · 3 H₂O
• Numéro CAS: 121268-17-5
• Poids moléculaire : 325.12
• NACRES: NA.24
• PubChem Substance ID: 329748953
• UNSPSC Code: 41116107
• MDL number: MFCD01748233

Propriétés

• grade: pharmaceutical primary standard
• agency: USP
• API family: alendronate
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: [Na+].[H]O[H].[H]O[H].[H]O[H].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O
• InChI: 1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1
• InChI key: DCSBSVSZJRSITC-UHFFFAOYSA-M
• Gene Information: human ... FDPS(2224)

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

Alendronate sodium is a primary amino bisphosphonate.

Application

Alendronate sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Alendronate sodium trihydrate is a bone resorption inhibitor; farnesyl diphosphate synthase inhibitor (IC₅₀ = 460 nM); CD45 protein tyrosine phosphatase inhibitor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable