Z0153

ZM 241385

≥98% (HPLC), adenosine A2A antagonist, powder

• Synonyme(s) : 4-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol
• Formule empirique (notation de Hill) : C₁₆H₁₅N₇O₂
• Numéro CAS: 139180-30-6
• Poids moléculaire : 337.34
• UNSPSC Code: 12352200
• PubChem Substance ID: 329831597
• NACRES: NA.77
• MDL number: MFCD00908394
• Assay: ≥98% (HPLC)
• Form: powder

Propriétés

• Nom du produit: ZM 241385, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: >15 mg/mL
• storage temp.: room temp
• SMILES string: Nc1nc(NCCc2ccc(O)cc2)nc3nc(nn13)-c4ccco4
• InChI: 1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)
• InChI key: PWTBZOIUWZOPFT-UHFFFAOYSA-N

Description

Biochem/physiol Actions

ZM 241385 is a potent selective adenosine A2A antagonist.

ZM 241385 is a potent selective adenosine A2A antagonist. The A2A receptor plays a role in regulating myocardial oxygen consumption and coronary blood flow and is highly expressed in the brain, where it has important roles in the regulation of glutamate and dopamine release. ZM 241385 has neuroprotective effects and is being investigated for use in Parkinson′s and other neurodegenerative disorders.

Features and Benefits

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable