U2625

Uric acid

≥99%, crystalline

• Synonyme(s) : 2,6,8-Trihydroxypurine
• Formule empirique (notation de Hill) : C₅H₄N₄O₃
• Numéro CAS: 69-93-2
• Poids moléculaire : 168.11
• UNSPSC Code: 12352005
• NACRES: NA.55
• PubChem Substance ID: 24900634
• EC Number: 200-720-7
• Beilstein/REAXYS Number: 156158
• MDL number: MFCD00005712
• Assay: ≥99%
• Form: crystalline

Propriétés

• Quality Segment: 100, 200
• assay: ≥99%
• form: crystalline
• mp: >300 °C (lit.)
• SMILES string: O=C1NC(=O)C2=C(N1)NC(=O)N2
• InChI: 1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)
• InChI key: LEHOTFFKMJEONL-UHFFFAOYSA-N

Description

Application

Uric acid has been used:

• in inducing hyperuricemia in mice
• as a component of digestion fluid for the simulation of in vitro human digestion model
• in selectivity test of the glucose sensor in sweat-based diabetes monitoring

Biochem/physiol Actions

Uric acid is an insoluble catabolite produced by adenine and guanine metabolism. Accumulation of uric acid leads to gout, hyperuricemia, arthritis and renal failure. Elevated uric acid levels contributes to hypertension and pathogenesis of cardiovascular disease. Low uric acid levels associated with Parkinson′s disease and multiple sclerosis, may elicit protective functionality. High levels of uric acid in patients with chronic obstructive pulmonary disease (COPD) may serve as potential marker for diagnosis.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)