T7313

1-[2-(Trifluoromethyl)phenyl]imidazole

• Synonyme(s) : TRIM
• Formule empirique (notation de Hill) : C₁₀H₇F₃N₂
• Numéro CAS: 25371-96-4
• Poids moléculaire : 212.17
• NACRES: NA.77
• PubChem Substance ID: 24278754
• UNSPSC Code: 12352202
• MDL number: MFCD00041206

Propriétés

• biological source: synthetic (organic)
• Quality Segment: 200
• assay: ≥98% (GC)
• form: solid
• solubility: DMSO: soluble 30 mg/mL
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)c1ccccc1-n2ccnc2
• InChI: 1S/C10H7F3N2/c11-10(12,13)8-3-1-2-4-9(8)15-6-5-14-7-15/h1-7H
• InChI key: WZBWBNCQUTXYEL-UHFFFAOYSA-N
• Gene Information: human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)

Description

Biochem/physiol Actions

Potent nitric oxide synthase inhibitor.

Potent nitric oxide synthase inhibitor. Because of the putative involvement of nitric oxide in depression and stress syndromes, TRIM was studied for its antidepressant effects, and found to reduce manifestations of stress in an animal model as well as fluoxetine.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mot-clé: Warning
• Codes de danger: H315,H319,H335
• Mentions de précaution: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): dust mask type N95 (US), Eyeshields, Gloves