T1875

Testosterone propionate

solid

• Synonyme(s) : 17β-hydroxy-4-androstène-3-one 17-propionate, 4-androstène même-17β-ol-3-one 17-propionate
• Formule empirique (notation de Hill) : C₂₂H₃₂O₃
• Numéro CAS: 57-85-2
• Poids moléculaire : 344.49
• UNSPSC Code: 51111800
• NACRES: NA.77
• PubChem Substance ID: 24899994
• EC Number: 200-351-1
• Beilstein/REAXYS Number: 3221760
• MDL number: MFCD00003653
• Assay: ≥98% (HPLC)
• Form: solid

Propriétés

• biological source: synthetic (organic)
• Quality Segment: 200
• sterility: non-sterile
• assay: ≥98% (HPLC)
• form: solid
• drug control: USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
• color: white
• solubility: acetone: soluble 1 in 4 of acetone, chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow, ethanol: soluble 1 in 6 of ethanol, ethyl oleate: soluble 1 in 20 of ethyl oleate, propylene glycol: soluble 1 in 30 of propylene glycol, soluble 1 in 20 of ethyl oleate, ethanol: 10 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.4 mg/mL, H₂O: insoluble, oil: soluble
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])OC(=O)CC
• InChI: 1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1
• InChI key: PDMMFKSKQVNJMI-BLQWBTBKSA-N
• Gene Information: human ... AR(367), CYP17A1(1586) ; rat ... Ar(24208)

Description

Application

Testosterone propionate has been used for studying its effects on pregnant ewes,.

Biochem/physiol Actions

Androgens direct the development of the male phenotype during embryogenesis and at puberty. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone in the target tissues where it regulates several biological functions. Testosterone propionate has been synthetically derived from a plant. This product has extended and faster-acting functions when compared to other testosterone esters.

Physical form

Photosensitive solid

Preparation Note

This product is soluble in chloroform (50 mg/ml). It is also soluble in various oils. The oil solutions can be sterilized by maintaining at 150 deg C for 1 hour. It is practically insoluble in water, soluble 1 in 6 of ethanol, 1 in 4 of acetone, 1 in 20 of ethyl oleate, and 1 in 30 of propylene glycol. The product is incompatible with alkalis and oxidizing agents and it should be protected from light.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS07,GHS09
• Mot-clé: Danger
• Codes de danger: H302,H351,H360FD,H400
• Mentions de précaution: P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Repr. 1A
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Que se passe-t-il ?: WGK 3
• EPI (équipement de protection individuelle): Eyeshields, Gloves, type P3 (EN 143) respirator cartridges