T0557

Taurodéoxycholate de sodium hydrate

BioXtra, ≥97% (TLC)

• Synonyme(s) : Acide 2-([3α,12α-dihydroxy-24-oxo-5β-cholan-24-yl]amino)éthanesulfonique, Acide taurodéoxycholique sodium salt hydrate
• Formule linéaire : C₂₆H₄₄NO₆SNa · xH₂O
• Numéro CAS: 207737-97-1
• Poids moléculaire : 521.69 (anhydrous basis)
• UNSPSC Code: 12161900
• NACRES: NA.25
• PubChem Substance ID: 24899897
• MDL number: MFCD00149238
• Beilstein/REAXYS Number: 3901204

Propriétés

• description: anionic
• Quality Segment: 200
• product line: BioXtra
• assay: ≥97% (TLC)
• mol wt: micellar avg mol wt 3100
• aggregation number: 6
• impurities: ≤0.002% Phosphorus (P), ≤0.1% Insoluble matter
• CMC: 1-4 mM (20-25°C)
• solubility: H₂O: 0.5 M, clear, colorless to faintly yellow
• anion traces: chloride (Cl^-): ≤0.5%, sulfate (SO₄^2-): ≤0.05%
• cation traces: Al: ≤0.0005%, Ca: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.01%, Mg: ≤0.005%, NH₄⁺: ≤0.05%, Pb: ≤0.001%, Zn: ≤0.0005%
• SMILES string: O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
• InChI: 1S/C26H45NO6S.Na.H2O/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);;1H2/q;+1;/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;;/m1../s1
• InChI key: OLPIZAYYAVQETM-GGPRKOIFSA-M

Description

General description

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

Application

Détergent anionique apparenté aux sels biliaires, utilisé pour l′isolement de protéines membranaires, notamment les protéines de la membrane mitochondriale interne.

Sodium tauroursodeoxycholate has been used in a study to assess short-term feedback regulation of bile salt uptake in rodent liver. It has also been used in a study to investigate its potential to resolve endoplasmic reticulum (ER) stress in intestinal epithelial cells. It is also used for isolation of membrane proteins including inner mitochondrial membrane proteins.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): Eyeshields, Gloves, type N95 (US)