SML1537

Cantharidin Ready Made Solution

0.1 mg/mL in DMSO

• Synonyme(s) : 3a,7a-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione, 7a-Dimethylhexahydro-3a,4,7-epoxyisobenzofuran, Cantharidine, Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione
• Formule empirique (notation de Hill) : C₁₀H₁₂O₄
• Numéro CAS: 56-25-7
• Poids moléculaire : 196.20
• UNSPSC Code: 12352200
• EC Number: 200-664-3
• NACRES: NA.77
• Form: solution

Propriétés

• biological source: insect
• Quality Segment: 200
• form: solution
• concentration: 0.1 mg/mL in DMSO
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: O1[C@@H]2[C@]3([C@@]([C@H]1CC2)(C(=O)OC3=O)C)C
• InChI: 1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10-
• InChI key: DHZBEENLJMYSHQ-XCVPVQRUSA-N

Description

Biochem/physiol Actions

Cantharidin inhibits protein phosphatase 2A.

It is a component of mylabris, a traditional Chinese medicine. Cantharidin exhibits anti-tumor activity. In addition, cantharidin can work against multidrug-resistant cells. In the epidermis, it causes release of neutral serine proteases, leading to degeneration of the desmosmal plaque. This results in acantholysis and intraepidermal blistering as well as skin lysis. PP2A is involved in the cell cycle, cell death, growth and cell-fate determination.

Other Notes

Stable for at least two years at 2-8° C.

Informations sur la sécurité

• Classe de stockage: 10 - Combustible liquids
• Que se passe-t-il ?: WGK 1
• Point d'éclair (°F): 188.6 °F
• Point d'éclair (°C): 87 °C