SML1480

Alclometasone dipropionate

≥98% (HPLC)

• Synonyme(s) : Alclometasone Dipropanoate, Sch 22219, (7α,11β,16α)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione, 7α-Chloro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate), Alclometasone 17,21-dipropionate
• Formule empirique (notation de Hill) : C₂₈H₃₇ClO₇
• Numéro CAS: 66734-13-2
• Poids moléculaire : 521.04
• UNSPSC Code: 12352200
• EC Number: 266-464-3
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propriétés

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: Cl[C@H]1[C@@H]2[C@@H]([C@@]4(C(=CC(=O)C=C4)C1)C)[C@H](C[C@]3([C@H]2C[C@H]([C@]3(OC(=O)CC)C(=O)COC(=O)CC)C)C)O
• InChI: 1S/C28H37ClO7/c1-6-22(33)35-14-21(32)28(36-23(34)7-2)15(3)10-18-24-19(29)12-16-11-17(30)8-9-26(16,4)25(24)20(31)13-27(18,28)5/h8-9,11,15,18-20,24-25,31H,6-7,10,12-14H2,1-5H3/t15-,18+,19-,20+,24-,25+,26+,27+,28+/m1/s1
• InChI key: DJHCCTTVDRAMEH-DUUJBDRPSA-N

Description

Biochem/physiol Actions

Alclometasone dipropionate is a glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, immunosuppressive, antipruritic, and vasoconstrictive effects of natural glucocorticoids.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mot-clé: Warning
• Codes de danger: H361
• Mentions de précaution: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable