SML1252

Treosulfan

≥98% (HPLC), Alkylating agent, powder

• Synonyme(s) : (2S,3S)-Butanetetraol 1,4-dimesylate, (2S,3S)-Threitol 1,4-bismethanesulfonate, L-Threitol 1,4-bis(methanesulfonate), NSC 39069, Threosulphan, Treosulphan
• Formule empirique (notation de Hill) : C₆H₁₄O₈S₂
• Numéro CAS: 299-75-2
• Poids moléculaire : 278.30
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Propriétés

• Nom du produit: Treosulfan, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -4.9 to -5.9°, c = 1 in acetone
• color: white to beige
• solubility: H₂O: 5 mg/mL, clear
• storage temp.: −20°C
• SMILES string: [S](=O)(=O)(OCC(O)C(O)CO[S](=O)(=O)C)C
• InChI: 1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3
• InChI key: YCPOZVAOBBQLRI-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Alkylating agent, anti-neoplastic agent

Treosulfan is a biofunctional alkylating agent.

Treosulfan is bifunctional alkylating agent.

Treosulfan/l-threitol-1,4-bis-methanesulfonate; dihydroxybusulfan; NSC 39069. It is a prodrug of a bifunctional alkylating cytotoxic agent. Treosulfan can be activated non-enzymatically to two active epoxides. It is used to treat ovarian cancer.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mot-clé: Danger
• Codes de danger: H340,H350,H361f
• Mentions de précaution: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 1A - Muta. 1B - Repr. 2
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable