SML1195

Palonosetron hydrochloride

≥98% (HPLC)

• Synonyme(s) : RS 25259-197, (3aS)-2-[(3S)-Quinuclidin-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one hydrochloride, (3aS)-2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-Benz[de]isoquinolin-1-one hydrochloride (1:1)
• Formule empirique (notation de Hill) : C₁₉H₂₄N₂O · HCl
• Numéro CAS: 135729-62-3
• Poids moléculaire : 332.87
• NACRES: NA.77
• PubChem Substance ID: 329825713
• UNSPSC Code: 12352200
• MDL number: MFCD00939524
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated, protect from light

Propriétés

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -90 to -110°, c = 0.4 in H₂O
• storage condition: desiccated, protect from light
• color: white to beige
• solubility: H₂O: 20 mg/mL, clear
• storage temp.: −20°C
• SMILES string: O=C1N([C@H]2C3CCN(CC3)C2)C[C@]4([H])C5=C1C=CC=C5CCC4.[H]Cl
• InChI: 1S/C19H24N2O.ClH/c22-19-16-6-2-4-14-3-1-5-15(18(14)16)11-21(19)17-12-20-9-7-13(17)8-10-20;/h2,4,6,13,15,17H,1,3,5,7-12H2;1H/t15-,17-;/m1./s1
• InChI key: OLDRWYVIKMSFFB-SSPJITILSA-N
• Gene Information: human ... HTR3A(3359)

Description

Biochem/physiol Actions

Palonosetron is a potent and selective 5-HT3 receptor antagonist (Aloxi) used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

Palonosetron is a potent and selective 5-HT3 receptor antagonist.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mot-clé: Warning
• Codes de danger: H302
• Mentions de précaution: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable