A working solution in dimethylsulfoxide (DMSO) can be stored at ?20°C.
Note to UGCMB: Please send directly to customer, duplicate
SML1068
TIC10 angular
≥98% (HPLC)
Synonyme(s) :
7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one., ONC-201, ONC201, TIC10 corrected
Se connecter pour consulter les tarifs organisationnels et contractuels.
Sélectionner une taille de conditionnement
Changer de vue
| Taille/Référence | Disponibilité | Prix |
|---|
A propos de cet article
Formule empirique (notation de Hill) :
C24H26N4O
Poids moléculaire :
386.49
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderQuality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear
storage temp.
2-8°C
General description
TIC10 (TRAIL-inducing compound 10) is an anticancer molecule also referred as ONC201.
Biochem/physiol Actions
TIC10 angular is a potent blood brain barrier penetrant and orally active inducer of TRAIL production that induces death of multiple human cancers.
TIC10 angular is a potent blood brain barrier penetrant and orally active inducer of TRAIL production that induces death of multiple human cancers. TIC10 angular inactivates both Akt and ERK, which results in Foxo3a nuclear factor migration to the nucleus and binding to TRAIL promoter.
Features and Benefits
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
1 of 1
Cet article | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥95% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 5 mg/mL, clear | solubility DMSO: 3 mg/mL, clear (warmed) | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear |
| color white to beige | color white to beige | color white to beige | color white to beige |
Mot-clé
Warning
Codes de danger
Mentions de précaution
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
Classe de stockage
11 - Combustible Solids
Que se passe-t-il ?
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
-
How long can I store a working solution in dimethylsulfoxide (DMSO) at −20°C?
1 answer-
Helpful?
-
-
What is storage temperature for 100 mM TIC10 in DMSO? 4 degrees or -20 degree?
1 answer-
A working solution in dimethylsulfoxide (DMSO) can be stored at −20°C.
Helpful?
-