SML0881

Rivastigmine tartrate

≥98% (HPLC), cholinesterase inhibitor, powder

• Synonyme(s) : ENA-713, Ethylmethyl-carbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester, N-Ethyl-N-methyl-carbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester tartrate, S-Rivastigmine tartrate
• Formule empirique (notation de Hill) : C₁₄H₂₂N₂O₂ · C₄H₆O₆
• Numéro CAS: 129101-54-8
• Poids moléculaire : 400.42
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Propriétés

• Nom du produit: Rivastigmine tartrate, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 15 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: N([C@@H](C)c1cc(ccc1)OC(=O)N(CC)C)(C)C.O[C@@H]([C@H](O)C(=O)O)C(=O)O
• InChI: 1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m00/s1
• InChI key: GWHQHAUAXRMMOT-RWALOXMOSA-N

Description

General description

Rivastigmine tartrate is a cholinesterase inhibitor. It is also called as exelon.

Application

Rivastigmine tartrate has been used in cholinesterase inhibition assay.

Biochem/physiol Actions

Rivastigmine is an orally available, brain penetrant, reversible cholinesterase inhibitor that enhances cognitive function in patients with Alzheimer′s and Parkinson′s diseases. Rivastigmine inhibits both butyrylcholinesterase and acetylcholinesterase.

Rivastigmine is an orally available, brain penetrant, reversible cholinesterase inhibitor.

Rivastigmine tartrate is used to treat Alzheimer′s disease. It helps to improve thinking ability. It helps to increase cholinergic function by inhibiting acetylcholinesterase.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Que se passe-t-il ?: WGK 3
• Pictogrammes: GHS06,GHS09
• Mot-clé: Danger
• Codes de danger: H300,H411
• Mentions de précaution: P264 - P270 - P273 - P301 + P310 - P391 - P405
• Hazard Classifications: Acute Tox. 2 Oral - Aquatic Chronic 2
• Classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable