SML0310

Tryptanthrin

≥98% (HPLC)

• Synonyme(s) : Couroupitine A, Indolo(2,1-b)quinazoline-6,12-dione, NSC 349447, Tryptanthrine
• Formule empirique (notation de Hill) : C₁₅H₈N₂O₂
• Numéro CAS: 13220-57-0
• Poids moléculaire : 248.24
• NACRES: NA.77
• PubChem Substance ID: 329825315
• UNSPSC Code: 12352200
• MDL number: MFCD00012073
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: protect from light

Propriétés

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: protect from light
• color: faintly yellow to dark yellow
• solubility: DMSO: 2 mg/mL (warmed)
• storage temp.: 2-8°C
• SMILES string: O=C1C2=NC3=CC=CC=C3C(N2C4=C1C=CC=C4)=O
• InChI: 1S/C15H8N2O2/c18-13-10-6-2-4-8-12(10)17-14(13)16-11-7-3-1-5-9(11)15(17)19/h1-8H
• InChI key: VQQVWGVXDIPORV-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Tryptanthrin is a plant alkaloid with anti-inflammatory and anti cancer activities.

Tryptanthrin is a plant alkaloid with anti-inflammatory and anti cancer activities. Tryptanthrin blocks leukotriene production in neutrophils and in whole blood assays, and in an in vivo rat pleurisy model. The compound also inhibits P-glycoprotein, and sensitizes resistant cancer cell lines to killing by cytotoxic agents.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mot-clé: Warning
• Codes de danger: H302
• Mentions de précaution: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable