SML0243

ML169

≥98% (HPLC)

• Synonyme(s) : 2-[[1-[(5-Bromo-2-fluorophenyl)methyl]-1H-indol-3-yl]sulfonyl]-N-(5-methyl-3-isoxazolyl)-acetamide, VU0405652
• Formule empirique (notation de Hill) : C₂₁H₁₇BrFN₃O₄S
• Numéro CAS: 1222878-02-5
• Poids moléculaire : 506.34
• NACRES: NA.77
• PubChem Substance ID: 329825253
• UNSPSC Code: 12352200
• MDL number: MFCD23704785
• Assay: ≥98% (HPLC)
• Form: powder

Propriétés

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: >5 mg/mL
• storage temp.: 2-8°C
• SMILES string: Cc1cc(NC(=O)CS(=O)(=O)c2cn(Cc3cc(Br)ccc3F)c4ccccc24)no1
• InChI: 1S/C21H17BrFN3O4S/c1-13-8-20(25-30-13)24-21(27)12-31(28,29)19-11-26(18-5-3-2-4-16(18)19)10-14-9-15(22)6-7-17(14)23/h2-9,11H,10,12H2,1H3,(H,24,25,27)
• InChI key: RUYRNYRGPSAXTK-UHFFFAOYSA-N

Description

Biochem/physiol Actions

ML169 is a positive allosteric modulator (PAM) of the muscarinic acetylcholine receptor M1 (CHRM1). ML169 does not cross react with other muscarinic receptors and is able to penetrate the blood brain barrier.

ML169 is a positive allosteric modulator of muscarinic acetylcholine receptor M1.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable