SMB01045

Isoliquiritin

≥90% (LC/MS-ELSD)

• Synonyme(s) : 4-beta-D-glucopyranosyloxy-2′,4′-dihydroxy-trans-chalcone, Isoliquiritoside
• Formule empirique (notation de Hill): C₂₁H₂₂O₉
• Numéro CAS: 5041-81-6
• Poids moléculaire : 418.39
• Numéro MDL: MFCD00272145
• Code UNSPSC : 12352205
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: plant
• Pureté: ≥90% (LC/MS-ELSD)
• Forme: solid
• Poids mol.: 418.39
• Application(s): metabolomics; vitamins, nutraceuticals, and natural products
• Température de stockage: −20°C
• InChI: 1S/C21H22O9/c22-10-17-18(26)19(27)20(28)21(30-17)29-13-5-1-11(2-6-13)3-8-15(24)14-7-4-12(23)9-16(14)25/h1-9,17-23,25-28H,10H2/b8-3+/t17-,18-,19+,20-,21-/m1/s1
• Clé InChI: YNWXJFQOCHMPCK-LXGDFETPSA-N

Description

Description générale

Isoliquiritin, also known as Isoliquiritoside, is a flavonoid belongs to the class of dihydrochalcones commonly available from Glycyrrhiza Sp. plants. This plant metabolite exhibits various biological activities, including antioxidant, antifungal, anti-HIV, anticancer properties.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Actions biochimiques/physiologiques

Isoliquiritin triggers apoptotic cell death by increasing the levels of p53 and p21 in A549 non-small cell lung cancer cells while also inhibiting the p53-dependent pathway and revealing interactions with Akt activities. Futher, Isoliquiritin has demonstrated neuroprotective activity against oxidative stress and has the capability to restrain the growth of microbial pathogens.

Caractéristiques et avantages

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Autres remarques

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable