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Key Documents

SAE0214

Sigma-Aldrich

Leucoagglutinin from P. vulgaris, recombinant

Expressed in P. pastoris, lyophilized powder, suitable for cell culture

Synonyme(s) :

PHA-L, Phytohemagglutinin-L, Red Kidney Bean Lectin

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About This Item

Code UNSPSC :
12352202
Nomenclature NACRES :
NA.21

Niveau de qualité

Forme

lyophilized powder

Numéro d'accès UniProt

Conditions d'expédition

wet ice

Température de stockage

-10 to -25°C

Description générale

Lectin from Red Kidney Bean has long been used in a wide variety of applications that require carbohydrate binding including but not limited to T-cell proliferation, leucoagglutination, glycoconjugate capture and more. The native form of lectin from Red Kidney Bean is composed of 2 isolectins (PHA-L and PHA-E) which combine in heterotetromeric combinations that elicit a variety of properties. This recombinant form is strictly the leucoagglutinin (PHA-L) isolectin only, so the erythroagglutinin (PHA-E) isolectin is absent in this product. This allows for more selective performance because there is no chance of PHA-E contamination as seen in native source products.

Actions biochimiques/physiologiques

Kidney bean lectin has a history of being used as a phytohemagglutinin because of its ability to agglutinate blood cells. This isolectin (PHA-L) specficially is the Leucoagglutinin type and can be used for leucoagglutination and as a mitogen. As a lectin, it is known to have some selectivity for binding of β1-6 branched N-glycans.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

A Useful Guide to Lectin Binding: Machine-Learning Directed Annotation of 57 Unique Lectin Specificities
Daniel Bojar
ACS Chemical Biology, 17(11), 2993-3012 (2022)

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