SAB4504044

Anti-phospho-Myosin regulatory light chain 2 (pSer¹⁸) antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-CMH10, Anti-MFM12, Anti-MLC-2s/v, Anti-MLC2
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 19 kDa
• Espèces réactives: human, rat, mouse
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P24844
• Numéro d'accès UniProt: P10916
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pSer18)
• Informations sur le gène: human ... MYL2(4633)

Description

Description générale

MYL2 (myosin light chain 2) encodes a myosin regulatory light chain (MLC-2V). It is made of two heavy chains, two essential light chains and two regulatory light chains. It is located on human chromosome 12q24.

Immunogène

The antiserum was produced against synthesized peptide derived from human Myosin regulatory light chain 2 around the phosphorylation site of Ser18.

Immunogen Range: 3-52

Actions biochimiques/physiologiques

MYL2 (myosin light chain 2) helps to convert energy from ATP hydrolysis into mechanical force. This gene also plays a major role in the growth and progression of chronic HF (heart failure). Mutation in MYL2 gene result in infantile type I muscle fibre disease and cardiomyopathy.

Caractéristiques et avantages

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Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable