S9012

Sulforhodamine B sodium salt

Powder

• Synonyme(s) : Acid red 52; Acid Rhodamine B
• Formule empirique (notation de Hill) : C₂₇H₂₉N₂NaO₇S₂
• Numéro CAS: 3520-42-1
• Poids moléculaire : 580.65
• UNSPSC Code: 12171500
• NACRES: NA.47
• PubChem Substance ID: 24899824
• EC Number: 222-529-8
• MDL number: MFCD00010180
• Colour Index Number: 45100
• Beilstein/REAXYS Number: 3886008

Propriétés

• Nom du produit: Sulforhodamine B sodium salt, Technical grade
• Quality Segment: 200
• form: powder
• composition: Dye content, ~75%
• εmax: ≥85000 at 554-560 nm
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [Na+].CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccc(cc4S([O-])(=O)=O)S([O-])(=O)=O)=[N+](\CC)CC)c1
• InChI: 1S/C27H30N2O7S2.Na/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35;/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1
• InChI key: SXQCTESRRZBPHJ-UHFFFAOYSA-M

Description

General description

Sulforhodamine B (also known as SRB, kiton rhodamine B, lissamine rhodamine B, or sulphorhodamine B) is a bright-pink anionic, aminoxanthene dye carrying two sulfonate substituents.

Application

Sulforhodamine B (SRB) is known for use in SRB assay for the determination of in vitro cytotoxicity through staining and the observation of live cells, proliferation and drug screening.

It has been used in the SRB assay to evaluate the effect of mouthwashes on protein content in primary cultures of human fibroblasts.

It is also suitable as a microscopic tracer for the assessment of blood-brain barrier integrity by post mortem inspection of frozen sections. SRB is useful as a caries detector dye with subsequent inspection of histological material.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)