RAB0472

Human TIMP-2 ELISA Kit

for serum, plasma, cell culture supernatant and urine

• Synonyme(s) : Metalloproteinase inhibitor 2 , TIMP-2, Tissue inhibitor of metalloproteinases 2
• NACRES: NA.32
• UNSPSC Code: 41116158
• Gene information: human ... TIMP2(7077)
• Input: sample type urine; sample type cell culture supernatant(s); sample type serum; sample type plasma
• Species reactivity: human
• Storage temp.: −20°C
• Shipped in: wet ice

Propriétés

• species reactivity: human
• packaging: kit of 96 wells (12 strips x 8 wells)
• technique(s): ELISA: suitable, capture ELISA: suitable
• input: sample type urine; sample type cell culture supernatant(s); sample type serum; sample type plasma
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 2 pg/mL; standard curve range: 1.6-1200 pg/mL
• detection method: colorimetric
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... TIMP2(7077)

Description

General description

The Human TIMP-2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human TIMP-2 in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human TIMP2

Application

For research use only. Not for use in diagnostic procedures.
Human TIMP-2 ELISA Kit has been used to measure tissue inhibitor of metalloproteinase-2 (TIMP-2) level in blood samples from Atherosclerotic renal artery stenosis (ARAS) patients.

Biochem/physiol Actions

Tissue inhibitor of metalloproteinase-2 (TIMP-2) plays a vital role in inhibition of matrix metalloproteinases (MMPs) and functions as a key modulator of extracellular matrix deposition and degradation in various physiological processes. TIMP-2 can also act through a matrix metalloproteinase (MMP)-independent mechanism inhibiting endothelial cell proliferation in vitro. TIMP-2 mediates anti-angiogenic activities in vivo. TIMP-2 is a target gene of the microRNA-miR-22. TIMP-2 functions as a biomarker for cell cycle arrest.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Informations sur la sécurité

• pictograms: GHS05
• signalword: Warning
• hcodes: H290
• pcodes: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Classe de stockage: 10 - Combustible liquids