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Merck

P5155

Acide D-pantothénique hemicalcium salt

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

Synonyme(s) :

(R)-(+)-N-(2,4-Dihydroxy-3,3-diméthyl-1-oxobutyl)-β-alanine hemicalcium salt, Vitamine B5

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A propos de cet article

Formule linéaire :
HOCH2C(CH3)2CH(OH)CONHCH2CH2CO2 ·1/2Ca
Numéro CAS:
Poids moléculaire :
238.27
NACRES:
NA.75
PubChem Substance ID:
eCl@ss:
34058012
UNSPSC Code:
12352205
EC Number:
205-278-9
MDL number:
Beilstein/REAXYS Number:
3769272
Assay:
≥98% (TLC)
Form:
powder
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biological source

synthetic (organic)

Quality Segment

product line

BioReagent

assay

≥98% (TLC)

form

powder

mol wt

Mw 238.27 g/mol

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

color

white to off-white

pH

7.0-8 (25 °C, 50 g/L)

solubility

water: soluble 50 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO

InChI

1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1

InChI key

FAPWYRCQGJNNSJ-UBKPKTQASA-L

General description

Plants and microorganisms, such as Escherichia coli are the major sources of D-pantothenic acid. It is water soluble and quite stable to heating.
En raison du caractère instable, hygroscopique, de l′acide libre, on utilise le sel de calcium.

Application

D-Pantothenic acid hemicalcium salt has been used:
  • as a component of FMX-turbodoma- derived media
  • as a supplement in DMEM (Dulbecco′s modified eagle media)/F-12 used for cell proliferation
  • as a supplement in preadipocyte media

Précurseur dans la biosynthèse du coenzyme A.

Biochem/physiol Actions

Along with coenzyme A (CoA, D-pantothenic acid is a precursor for acyl carrier protein. These are essential cofactors involved in fat, protein and carbohydrate metabolism. It also participates in the formation of acetylcholine neurotransmitter. D-pantothenic acid is considered as a source of nutrition and possesses immune function by mediating antibody formation. The production of cortisone is supported by D-pantothenic acid. It is essential for adrenal gland activity.


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Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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