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P1922

Sigma-Aldrich

Monoclonal Anti-Progesterone antibody produced in rat

clone 2H4, tissue culture supernatant

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About This Item

Numéro MDL:
MFCD00165530
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rat

Niveau de qualité

200

Conjugué

unconjugated

Forme d'anticorps

tissue culture supernatant

Type de produit anticorps

primary antibodies

Clone

2H4, monoclonal

Technique(s)

indirect ELISA: 1:1000 - 1:2000 (using Progesterone-BSA for coating.)
radioimmunoassay: suitable

Isotype

IgG1

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Description générale

Progesterone or P4 (pregn-4-ene-3,20-dione) is a female steroid hormone that belongs to the hormones class, progestogens. It is produced by majorly by ovaries, adrenal glands and placenta of humans and other species. Progesterone derived from placenta and corpus luteum is required for the maintenance of pregnancy. Progesterone inhibits the T cell mediated immune response involved in tissue rejection. The progesterone levels in females are low before ovulation and are elevated during the luteal phase. Monoclonal Anti-Progesterone antibody is IgG1 isotype purified from rat cell culture supernatant.

Immunogène

progesterone-7-BSA.

Application

The antibody may be used in various immunochemical techniques including ELISA, radioimmunoassay AND RIA to measure progesterone levels in milk.

Remarque sur l'analyse

dextran coated charcoal 3H RIA.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Letizia Debertolis et al.
Journal of veterinary science, 17(2), 189-197 (2015-12-10)
This study was conducted to evaluate the effects of induced endometritis on uterine blood flow in cows. Transrectal Doppler sonography was performed on uterine arteries of six cyclic cows before and for 4 days after inducing acute endometritis by intrauterine
Julia Jenikejew et al.
Conservation physiology, 9(1), coab098-coab098 (2022-01-07)
Progesterone and oestrogen are the main gonadal steroid hormones that regulate the ovarian activity and induce the fertile oestrus period in females. The monitoring of this receptive phase is particularly decisive for captive breeding and is commonly based on the
J S Mitchell et al.
Journal of dairy science, 87(9), 2864-2867 (2004-09-18)
The objectives were to develop a novel protein conjugate-based ELISA test for whole milk progesterone with a dynamic range capable of fully profiling estrous cycles in the dairy cow and to study effects of whole milk medium on antibody binding
Steroids.
N Applezweig
Chemical week, 104, 57-72 (1969-05-17)
Alexandre Azevedo et al.
Conservation physiology, 8(1), coaa075-coaa075 (2020-08-28)
Knowledge on species' reproductive biology is a fundamental pre-requisite of every conservation effort, but is often lacking. Sex steroids can provide valuable information for the assessment of reproductive success, whereas glucocorticoids are used to assess adrenocortical activity and stress-related bodily
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