P1851

PIPES

BioPerformance Certified, suitable for cell culture

• Synonyme(s) : Acide 1,4-pipérazinediéthanesulfonique, Acide pipérazine-N,N′-bis(2-éthanesulfonique), Pipérazine-1,4-bis(acide 2-éthanesulfonique)
• Formule empirique (notation de Hill) : C₈H₁₈N₂O₆S₂
• Numéro CAS: 5625-37-6
• Poids moléculaire : 302.37
• UNSPSC Code: 12161700
• NACRES: NA.25
• PubChem Substance ID: 24898249
• EC Number: 227-057-6
• Beilstein/REAXYS Number: 817713
• MDL number: MFCD00006159

Propriétés

• Quality Segment: 400
• grade: BioPerformance Certified, Molecular Biology
• form: crystalline powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin and Total Aerobic Microbial Count, tested
• useful pH range: 6.1-7.5
• pKa (25 °C): 6.8
• mp: >300 °C (lit.)
• solubility: 1 M NaOH: 20 + 80 mL g, clear, colorless, soluble
• application(s): diagnostic assay manufacturing
• foreign activity: DNAse, Exonuclease; NICKase, Endonuclease; RNAse; Protease, none detected
• SMILES string: OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
• InChI key: IHPYMWDTONKSCO-UHFFFAOYSA-N

Description

Application

• Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics.: The use of PIPES buffer in this study was integral to maintaining the stability of immunoglobulin G during differential scanning fluorimetry. This method is crucial for evaluating the stability of antibody-based therapeutics (Moggridge et al., 2017).

Informations sur la sécurité

• Classe de stockage: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)