P0130

Progesterone

≥99% (HPLC), powder, maturation of the uterine endothelium inducer

• Synonyme(s) : 4-Pregnene-3,20-dione
• Formule empirique (notation de Hill) : C₂₁H₃₀O₂
• Numéro CAS: 57-83-0
• Poids moléculaire : 314.46
• NACRES: NA.77
• PubChem Substance ID: 24278618
• UNSPSC Code: 51111800
• EC Number: 200-350-6
• MDL number: MFCD00003658
• Beilstein/REAXYS Number: 1915950
• Assay: ≥99%
• Form: powder

Propriétés

• Nom du produit: Progesterone, ≥99%
• biological source: synthetic (organic)
• Quality Segment: 300
• sterility: non-sterile
• assay: ≥99%
• form: powder
• mp: 128-132 °C (lit.)
• solubility: chloroform: 50 mg/mL, clear, colorless to light yellow
• originator: Abbott
• shipped in: ambient
• storage temp.: room temp
• SMILES string: CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
• InChI key: RJKFOVLPORLFTN-LEKSSAKUSA-N
• Gene Information: human ... ABCB1(5243), AR(367), CYP2C9(1559), EBP(10682), ESR1(2099), ESR2(2100), NR3C1(2908), NR3C2(4306), PGR(5241), SERPINA6(866) ; mouse ... Esr1(13982) ; rat ... Ar(24208), Nr3c1(24413), Pgr(25154)

Description

Biochem/physiol Actions

Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.

Induit la maturation et l′activité secrétoire de l′endothélium utérin ; supprime l′ovulation.

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Steroid hormone produced by the corpus luteum.

Informations sur la sécurité

• pictograms: GHS08
• signalword: Danger
• hcodes: H351,H360FD,H362
• pcodes: P202 - P260 - P263 - P264 - P270 - P308 + P313
• Hazard Classifications: Carc. 2 - Lact. - Repr. 1A
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges