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O1391

Sigma-Aldrich

Oil Red O solution

0.5% in isopropanol

Synonyme(s) :

Solvent Red 27, Sudan Red 5B

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About This Item

Formule empirique (notation de Hill):
C26H24N4O
Numéro CAS:
Poids moléculaire :
408.49
Numéro CE :
Code UNSPSC :
12171500
Nomenclature NACRES :
NA.47

Forme

liquid

Niveau de qualité

Concentration

0.5% in isopropanol

Couleur

dark red

εmax

0.20-0.50 at 510-517 nm

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

room temp

InChI

1S/C26H24N4O/c1-16-9-10-17(2)22(13-16)27-28-23-14-19(4)24(15-18(23)3)29-30-26-21-8-6-5-7-20(21)11-12-25(26)31/h5-15,29H,1-4H3/b28-27?,30-26-

Clé InChI

HJAYEODIXUYVIC-LTFAAIOASA-N

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Description générale

Oil Red O stains lipid materials and imparts red-orange color to the lipids. It also marks vacuoles, particularly observed in ALL-L3 (acute lymphoblastic leukemia) or Burkitt′s lymphoma/leukemia. Oil Red O staining is done on fresh samples, as alcohol fixation removes lipids.

Application

Oil red O solution has been used to stain neutral lipids and adipocytes and to visualize fat droplets in fibroblasts.
Oil red O is a lysochrome (fat-soluble dye) diazo dye used for staining of neutral triglycerides and lipids on frozen sections and some lipoproteins on paraffin sections. In histology, a supersaturated solution of oil red O in isopropanol may be used to stain fat in tissue.

Pictogrammes

FlameExclamation mark

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Organes cibles

Central nervous system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

53.6 °F - closed cup

Point d'éclair (°C)

12.0 °C - closed cup


Certificats d'analyse (COA)

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Zhang W, et al.
Alcoholism, Clinical and Experimental Research, 40(5), 988-999 (2016)
LWW Doody's all reviewed collection, McClatchey: Clinical Laboratory Medicine
Clinical Laboratory Medicine (2002)
Directly reprogramming fibroblasts into adipogenic, neurogenic and hepatogenic differentiation lineages by defined factors.
Wu W, et al.
Experimental and Therapeutic Medicine, 13(6), 2685-2690 (2017)
Sulforaphane inhibits mammary adipogenesis by targeting adipose mesenchymal stem cells.
Li Q, et al.
Breast Cancer Research and Treatment, 141(2), 317-324 (2013)
Guokai Yan et al.
Scientific reports, 7(1), 1914-1914 (2017-05-17)
Leucine (Leu) is a multifunctional essential amino acid that plays crucial role in various cellular processes. However, the integral effect of Leu on the hepatic proteome remains largely unknown. Here, we for the first time applied an isobaric tags for

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