N9876

4-Nitrophenyl butyrate

lipase substrate, chromogenic, esterase substrate, ≥98%, liquid

• Synonyme(s) : p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester
• Formule empirique (notation de Hill) : C₁₀H₁₁NO₄
• Numéro CAS: 2635-84-9
• Poids moléculaire : 209.20
• NACRES: NA.83
• PubChem Substance ID: 24897915
• UNSPSC Code: 12352204
• MDL number: MFCD00047734
• Beilstein/REAXYS Number: 1879729

Propriétés

• Nom du produit: 4-Nitrophenyl butyrate, ≥98%
• assay: ≥98%
• form: liquid
• density: 1.19 g/mL at 20 °C (lit.)
• storage temp.: −20°C
• SMILES string: CCCC(=O)Oc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C10H11NO4/c1-2-3-10(12)15-9-6-4-8(5-7-9)11(13)14/h4-7H,2-3H2,1H3
• InChI key: DVDUMIQZEUTAGK-UHFFFAOYSA-N

Description

General description

4-Nitrophenyl butyrate is a substrate for esterase, and lipase enzyme. Hydrolysis of 4-nitrophenyl butyrate by these enzymes releases the chromophore, 4-nitrophenolate which is spectrophotometrically analysed at 415 nm.

Application

4-nitrophenyl butyrate has been used:

• as a substrate for esterase activity in monocyte-derived macrophage cell line in response to polyethylene
• as a substrate for mycobacterial phospholipase A and mycobacterial cutinase activity
• as a substrate to determine the effect of buffers and solvents on human carboxylesterase

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Classe de stockage: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter