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M6502

Sigma-Aldrich

6-Methylpurine

≥99%

Synonyme(s) :

MeP

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About This Item

Formule empirique (notation de Hill):
C6H6N4
Numéro CAS:
2004-03-7
Poids moléculaire :
134.14
Numéro CE :
217-903-2
Numéro MDL:
MFCD00083663
Code UNSPSC :
41106305
ID de substance PubChem :
24897013
Nomenclature NACRES :
NA.51

Source biologique

synthetic (organic)

Pureté

≥99%

Forme

powder

Pf

237-238 °C (lit.)

Solubilité

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

Température de stockage

−20°C

Chaîne SMILES 

Cc1ncnc2[nH]cnc12

InChI

1S/C6H6N4/c1-4-5-6(9-2-7-4)10-3-8-5/h2-3H,1H3,(H,7,8,9,10)

Clé InChI

SYMHUEFSSMBHJA-UHFFFAOYSA-N

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Application

6-Methylpurine (MeP) is a toxic adenine analog used as a bisubstrate inhibitor of enzymes that bind adenosyl moieties and which may become phosphorylated to levels that inhibit RNA and protein synthesis.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Paromita Chakraborty et al.
Environmental pollution (Barking, Essex : 1987), 249, 1071-1080 (2019-05-31)
The Hooghly River (HR) estuary is the first deltaic off-shoot of the perennial and transboundary river, Ganga, India. HR receives industrial and domestic waste along with storm-water run-off from Kolkata city and the adjoining districts. Organic micropollutants (OMPs) have been
L J Lockett et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 3(11), 2075-2080 (1998-11-17)
Enzyme-prodrug therapy for the treatment of cancer is an experimental procedure that is under intensive investigation. However, the relative merits of the various systems for use under specific conditions are still being determined. We have compared the efficacy of cell
Hoonsik Yoom et al.
The Science of the total environment, 634, 677-686 (2018-04-12)
The reaction kinetics, products, and pathways of methylparaben (MeP) during water chlorination with and without bromide (Br-) were investigated to better understand the fate of parabens in chlorinated waters. During the chlorination of MeP-spiked waters without Br-, MeP was transformed
Yingxin Yu et al.
Ecotoxicology and environmental safety, 182, 109419-109419 (2019-07-14)
Parabens are a kind of preservatives widely used in cosmetic and personal care products and ubiquitously detected in the environment. However, little is known on human exposure to these chemicals. Our study mainly investigated the urinary parabens in adults from
H Ohgaki et al.
Journal of cancer research and clinical oncology, 117(1), 13-18 (1991-01-01)
The formation of O6-methyldeoxyguanosine (O6-MedGuo) was determined by an immuno-slot-blot assay in DNA of various tissues of F344 rats exposed to N-methyl-N-nitrosourea (MNU) in the drinking water at 400 ppm for 2 weeks. Although the pyloric region of the glandular
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