M0443

Mirtazapine

≥98% (HPLC), 5-HT2 antagonist; 5-HT3, H1 and α2 antagonist, powder

• Synonyme(s) : 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
• Formule empirique (notation de Hill) : C₁₇H₁₉N₃
• Numéro CAS: 85650-52-8
• Poids moléculaire : 265.35
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724531
• NACRES: NA.77
• MDL number: MFCD00865427
• Assay: ≥98% (HPLC)
• Form: powder

Propriétés

• Nom du produit: Mirtazapine, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white
• solubility: DMSO: 8 mg/mL, clear
• SMILES string: CN1CCN2C(C1)c3ccccc3Cc4cccnc24
• InChI: 1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
• InChI key: RONZAEMNMFQXRA-UHFFFAOYSA-N
• Gene Information: human ... ADRA2A(150), ADRA2B(151), ADRA2C(152), DRD2(1813), DRD3(1814), DRD4(1815), HRH1(3269), HTR1A(3350), HTR2A(3356), HTR2C(3358), HTR7(3363) ; mouse ... Slc6a2(20538) ; rat ... Adra1a(29412), Drd1a(24316), Drd2(24318), Htr1a(24473), Htr2a(29595), Htr2c(25187), Slc6a3(24898), Slc6a4(25553)

Description

Biochem/physiol Actions

Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). Mirtazapine agonizes selective adrenergic and serotonergic receptors so that both NE release and 5-HT_1A mediated serotonergic signaling are increased.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mot-clé: Warning
• Codes de danger: H302,H336
• Mentions de précaution: P261 - P264 - P270 - P271 - P301 + P312 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Oral - STOT SE 3
• Organes cibles: Central nervous system
• Classe de stockage: 11 - Combustible Solids
• Que se passe-t-il ?: WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• EPI (équipement de protection individuelle): Eyeshields, Gloves, type N95 (US)