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L9045

Lipodisq®

Styrene:Maleic Anhydride Copolymer 3:1

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A propos de cet article

NACRES:
NA.26
UNSPSC Code:
12352202
Form:
powder
Biological source:
synthetic
Service technique
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biological source

synthetic

Quality Segment

200

form

powder

storage temp.

room temp

General description

Lipodisq® reagents are novel polymers derived from styrene and maleic acid. Lipodisq® polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.

Application

Lipodisq® reagents are novel polymers derived from styrene and maleic acid. Lipodisq polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents. In general, Lipodisq polymers are potentially useful in mitigating the use of detergents for the solubilization of membrane proteins. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.
The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents.

Functional pH range: 6.0 - 9.0

Biochem/physiol Actions

Lipodisq® polymers are potentially useful in mitigating the use of detergents for solubilization of membrane proteins. Dissolving this product in an aqueous solution, with sufficient base (e.g. KOH, NaOH), causes hydrolysis of each anhydride moiety into two carboxylic acid/carboxylate groups. This action renders the SMA polymer soluble in aqueous media. Lipodisq® acts as a potential membrane mimic system.

Legal Information

Lipodisq is a registered trademark of Malvern Cosmeceutics Limited

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Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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