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Merck
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L3750

Sigma-Aldrich

β-Lactose

≤30% α-anomer basis, ≥99% total lactose basis

Synonyme(s) :

β-D-Gal-(1→4)-β-D-Glc

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About This Item

Formule empirique (notation de Hill):
C12H22O11
Numéro CAS:
5965-66-2
Poids moléculaire :
342.30
Numéro CE :
227-751-9
Numéro MDL:
MFCD00064521
Code UNSPSC :
12352201
ID de substance PubChem :
24896352
Nomenclature NACRES :
NA.25

Source biologique

bovine milk

Niveau de qualité

200

Pureté

≥99% total lactose basis

Forme

powder

Concentration

≥30% (α-anomer)

Couleur

white to off-white

Solubilité

water: 50 mg/mL, clear, colorless

Température de stockage

room temp

Chaîne SMILES 

OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11-,12+/m1/s1

Clé InChI

GUBGYTABKSRVRQ-DCSYEGIMSA-N

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Description générale

Lactose is an important disaccharide in human nutrition, culinary goods, and pharmaceuticals. β-lactose is an isomeric form that is rarely found in nature.

Application

β-Lactose has been used:
  • to treat HL-1 cells followed by phorbol dibutyrate (PDB) treatment to study if protein kinase C (PKC) -stimulated accumulation is mediated through galectin-3
  • as a component of a media to analyze the extracellular production of protein
  • along with recombinant galectin-3 to treat cells for the detection of galectin-3 cell surface binding
  • along with recombinant galectin-3 or a control protein to stimulate T cells for apoptosis assay

Actions biochimiques/physiologiques

Beta-Lactose is the beta-pyranose form of the compound lactose.
Lactose, an excipient in a various medication, is used as an additive in a variety of foods. It is utilized as a commercial additive in the food industry due to its texture, flavor, and adhesive characteristics.

Autres remarques

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

A tool for monitoring Trichoderma harzianum: I. Transformation with the GUS gene by protoplast technology
Thrane C, et al.
Phytopathology, 85(11), 1428-1435 (1995)
Benjamin D Grant et al.
Analytical chemistry, 92(16), 11305-11309 (2020-07-02)
The SARS-CoV-2 pandemic has created an unprecedented need for rapid diagnostic testing to enable the efficient treatment and mitigation of COVID-19. The primary diagnostic tool currently employed is reverse transcription polymerase chain reaction (RT-PCR), which can have good sensitivity and
Detlef Ritter et al.
Toxicology in vitro : an international journal published in association with BIBRA, 63, 104714-104714 (2019-11-11)
Due to the increasing need of new treatment options against bacterial lung infections, novel antimicrobial peptides (AMPs) are under development. Local bioavailability and less systemic exposure lead to the inhalation route of administration. Combining AMPs with nanocarriers (NCs) into nanosystems
Preparation and characterization of high purity anhydrous beta-Lactose from alpha-Lactose monohydrate at mild temperature
Lopez-Pablos AL, et al.
International Journal of Polymer Science (2018)
Logan K Smith et al.
eLife, 10 (2021-08-10)
Despite the mechanisms of central and peripheral tolerance, the mature B cell compartment contains cells reactive for self-antigen. How these cells are poised not to respond and the mechanisms that restrain B cell responses to low-affinity endogenous antigens are not
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