I5161

Iodoacétamide

• Formule linéaire : ICH₂CONH₂
• Numéro CAS: 144-48-9
• Poids moléculaire : 184.96
• EC Number: 205-630-1
• UNSPSC Code: 12352202
• NACRES: NA.21
• Beilstein/REAXYS Number: 1739080
• MDL number: MFCD00008028

Propriétés

• biological source: synthetic
• Quality Segment: 400
• assay: ≥99% (NMR)
• form: powder
• mp: 92-95 °C (lit.)
• solubility: H₂O: 0.5 M, clear, colorless
• suitability: suitable for manufacturing use
• application(s): downstream processes; pharma/biopharma processes; upstream processes
• storage temp.: 2-8°C
• SMILES string: NC(=O)CI
• InChI: 1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
• InChI key: PGLTVOMIXTUURA-UHFFFAOYSA-N

Description

General description

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Biochem/physiol Actions

L'iodoacétamide agit comme un réactif d'alkylation des résidus cystéine pour le séquençage des peptides. C'est un inhibiteur irréversible des enzymes présentant une cystéine au niveau de leur site actif. Il réagit beaucoup plus lentement avec les résidus histidine, mais cette activité entraîne l'inhibition de la ribonucléase.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS06,GHS08
• Mot-clé: Danger
• Codes de danger: H301,H317,H334,H413
• Mentions de précaution: P261 - P264 - P273 - P280 - P301 + P310 - P302 + P352
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable