H5659

L-histidine monohydrochloride monohydrate

98.5-101.0%, suitable for cell culture, BioXtra, non-animal source

• Synonyme(s) : Acide L-α-amino-β-(4-imidazolyl)propionique monohydrochloride
• Formule empirique (notation de Hill) : C₆H₉N₃O₂ · HCl · H₂O
• Numéro CAS: 5934-29-2
• Poids moléculaire : 209.63
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24895703
• NACRES: NA.26
• Beilstein/REAXYS Number: 4168261
• MDL number: MFCD00151027

Propriétés

• Nom du produit: L-histidine monohydrochloride monohydrate, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%
• biological source: non-animal source
• Quality Segment: 300
• agency: meets EP testing specifications
• product line: BioXtra
• assay: 98.5-101.0%
• form: crystalline powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white
• mp: 254 °C (dec.) (lit.)
• solubility: H₂O: 100 mg/mL
• SMILES string: O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
• InChI key: CMXXUDSWGMGYLZ-XRIGFGBMSA-N

Description

Application

L-Histidine monohydrochloride, non-animal, is used in cell culture media formulations used in biomanufacturing. The use of non-animal-sourced L-Histidine and other components avoids the risk of contaminating bioproducts with adventitious viruses.

L-Histidine monohydrochloride monohydrate has been used in bee cell culture medium.

Biochem/physiol Actions

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)