G4923

(E)-Guggulsterone

≥95% (HPLC), powder

• Synonyme(s) : (17E)-Pregna-4,17(20)-diene-3,16-dione
• Formule empirique (notation de Hill) : C₂₁H₂₈O₂
• Numéro CAS: 39025-24-6
• Poids moléculaire : 312.45
• NACRES: NA.77
• PubChem Substance ID: 329799934
• UNSPSC Code: 12352205
• MDL number: MFCD01310758

Propriétés

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• color: white to off-white
• solubility: DMSO: soluble 5 mg/mL
• functional group: ketone
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: C\C=C1\C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4-/t15-,17+,18+,20+,21-/m1/s1
• InChI key: WDXRGPWQVHZTQJ-AUKWTSKRSA-N

Description

Biochem/physiol Actions

Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.

Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.. Guggulsterone potently reverses multi-drug resistance in a number of human cancer cell lines, extending the efficacy of chemotherapy.

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H335,H412
• pcodes: P261 - P271 - P273 - P304 + P340 + P312 - P403 + P233 - P405
• Hazard Classifications: Aquatic Chronic 3 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable