F6127

Fludrocortisone acetate

synthetic, ≥98%, glucocorticoid activity, powder

• Synonyme(s) : 9α-Fluoro-11β,17α,21-trihydroxy-4-pregnene-3,20-dione acetate, 9-Fluorocortisol acetate, 9-Fluorohydrocortisone acetate
• Formule empirique (notation de Hill) : C₂₃H₃₁FO₆
• Numéro CAS: 514-36-3
• Poids moléculaire : 422.49
• NACRES: NA.77
• PubChem Substance ID: 24894899
• UNSPSC Code: 12352200
• EC Number: 208-180-4
• MDL number: MFCD00864160
• Assay: ≥98%
• Form: powder

Propriétés

• Nom du produit: Fludrocortisone acetate, ≥98%
• biological source: synthetic
• Quality Segment: 100
• sterility: non-sterile
• assay: ≥98%
• form: powder
• solubility: acetone: 50 mg/mL, clear, colorless to light yellow
• shipped in: ambient
• storage temp.: room temp
• SMILES string: CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C
• InChI: 1S/C23H31FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h10,16-18,27,29H,4-9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1
• InChI key: SYWHXTATXSMDSB-GSLJADNHSA-N
• Gene Information: human ... NR3C2(4306)

Description

General description

Fludrocortisone acetate is secreted by adrenal cortex. It increases the reabsorption of sodium and secretion of potassium and hydrogen. Fludrocortisone is used to treat cerebral salt wasting syndrome and adrenal insufficiency. Fludrocortisone improves the sensitivity of blood vessels to catecholamines and increases the blood volume.

Biochem/physiol Actions

Fludrocortisone acetate is a synthetic corticosteroid with more mineralocorticoid than glucocorticoid activity.

Informations sur la sécurité

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361
• pcodes: P201 - P301 + P312 + P330 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable