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F1553

S-(+)-Fluoxetine hydrochloride

Name: S-(+)-Fluoxetine hydrochloride
Brand: SIGMA

≥98% (HPLC), serotonin reuptake inhibitor, solid

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A propos de cet article

Formule empirique (notation de Hill) :

C₁₇H₁₈NOF₃ · HCl

Numéro CAS:

114247-06-2

Poids moléculaire :

345.79

UNSPSC Code:

12352200

PubChem Substance ID:

24278432

NACRES:

NA.77

MDL number:

MFCD04040001

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

desiccated

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Propriétés

Nom du produit

S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid

Quality Segment

100

assay

≥98% (HPLC)

form

solid

optical activity

[α]/D +14 to +19°, c = 1 in chloroform-d

storage condition

desiccated

color

white

solubility

H₂O: soluble ≥20 mg/mL

originator

Eli Lilly

storage temp.

room temp

SMILES string

Cl.CNCC[C@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2

InChI

1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m0./s1

InChI key

GIYXAJPCNFJEHY-NTISSMGPSA-N

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

Description

General description

Fluoxetine hydrochloride or fluoxetine hcl is a psychotropic agent and one of the initial members of the anti-depressant class of drugs known as selective serotonin-reuptake inhibitors (SSRIs). It is the active ingredient of Prozac^®.

Biochem/physiol Actions

Fluoxetine hcl (hydrochloride) is a selective serotonin reuptake inhibitor and functions as an antidepressant. This drug works at presynaptic terminals where it prevents the reuptake of serotonin, resulting in the accumulation of serotonin in extracellular fluid at synapses.

Selective serotonin reuptake inhibitor.

Features and Benefits

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Prozac is a registered trademark of Eli Lilly and Co.

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Cet article	F1678	F132	343290
Sigma-Aldrich F1553 S-(+)-Fluoxetine hydrochloride	Sigma-Aldrich F1678 R-(−)-Fluoxetine hydrochloride	Sigma-Aldrich F132 Fluoxétine hydrochloride	Sigma-Aldrich 343290 Fluoxetine, Hydrochloride
description ≥98% (HPLC), solid	description >98% (HPLC), solid	description solid	description A cell-permeable phenylpropylamine derived anti-depressant that acts as a selective serotonin re-uptake inhibitor (SSRI).
form solid	form solid	form solid	form solid
assay ≥98% (HPLC)	assay >98% (HPLC)	assay -	assay ≥98% (HPLC)
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 100
storage temp. room temp	storage temp. -	storage temp. -	storage temp. 2-8°C
solubility H₂O: soluble ≥20 mg/mL	solubility H₂O: soluble >10 mg/mL	solubility H₂O: 4 mg/mL, DMSO: >5 mg/mL	solubility water: 5 mg/mL, methanol: 100 mg/mL
storage condition desiccated	storage condition desiccated	storage condition -	storage condition OK to freeze, protect from light, desiccated (hygroscopic)

pictograms

GHS07,GHS09

signalword

Warning

hcodes

H302,H410

pcodes

P264 - P270 - P273 - P301 + P312 - P391 - P501

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c