E4375

(−)-Epinephrine (+)-bitartrate salt

solid, adrenergic receptor agonist

• Synonyme(s) : L-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol D-hydrogen bitartrate salt, L-Adrenaline (+)-bitartrate salt, L-Adrenaline D-hydrogentartrate, L-Epinephrine D-hydrogentartrate
• Formule empirique (notation de Hill): C₉H₁₃NO₃ · C₄H₆O₆
• Numéro CAS: 51-42-3
• Poids moléculaire : 333.29
• Numéro CE : 200-097-1
• Numéro MDL: MFCD00035077
• Code UNSPSC : 12352200
• ID de substance PubChem : 24277774
• Nomenclature NACRES : NA.77

Propriétés

• Nom du produit: (−)-Epinephrine (+)-bitartrate salt, solid
• Forme: solid
• Niveau de qualité: 200
• Couleur: white
• Solubilité: H₂O: soluble; alcohol: soluble
• Température de stockage: 2-8°C
• Chaîne SMILES: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CNC[C@H](O)c1ccc(O)c(O)c1
• InChI: 1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
• Clé InChI: YLXIPWWIOISBDD-NDAAPVSOSA-N
• Informations sur le gène: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)

Description

Description générale

Epinephrine is a hormone, which is also termed as adrenaline. It is a monoamine and catecholamine.[1]

Application

(-)Epinephrine (+)-bitartrate salt has been used:

• to test the possible existence of β-adrenergic vasodilation[2]
• to infuse into the adipose region to minimize blood loss and tissue contamination[3]
• as a platelet agonist in the preparation of optimal platelet aggregometry 96-well plates[4]
• in the measurement of total superoxide dismutase (tSOD) enzymatic activity[5]

Actions biochimiques/physiologiques

Adrenergic receptor agonist.

Epinephrine is mainly liberated from adrenal medulla in response to stress, that is facilitated through sympathetic fibers.[6]

Caractéristiques et avantages

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors, β-Adrenoceptors and Dopamine, Norepinephrine and Epinephrine Synthesis pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Attention

Light sensitive

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H300
• Conseils de prudence: P264 - P270 - P301 + P310 - P405 - P501
• Classification des risques: Acute Tox. 1 Oral
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges