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Merck
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Key Documents

E0502

Sigma-Aldrich

Elastin–Congo red

elastase substrate

Synonyme(s) :

Elastin Congo red

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About This Item

Numéro MDL:
MFCD00131000
Code UNSPSC :
12352204
Nomenclature NACRES :
NA.32

Forme

powder

Température de stockage

2-8°C

Description générale

Elastin−Congo red is a substrate-dye conjugate and is used in agar medium to probe elastase activity. The presence of elastase functionality leads to cleavage of the dye from the elastin substrate.

Application

Elastin−Congo red has been used as a substrate for neutrophil elastase, salivary elastase and P. aeruginosa.

Autres remarques

Elastin impregnated with Congo red dye.

Substrats

Substrate for the estimation of elastase.

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H350,H361d

Classification des risques

Carc. 1B - Repr. 2

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

Certificats d'analyse (COA)

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Elastase Substrate I, Colorimetric A specific chromogenic substrate for human neutrophil elastase.

Millipore

324696

Elastase Substrate I, Colorimetric

Congo Red BioXtra, certified by the Biological Stain Commission

Sigma-Aldrich

C6277

Congo Red

N-Succinyl-Ala-Ala-Ala-p-nitroanilide elastase substrate

Sigma-Aldrich

S4760

N-Succinyl-Ala-Ala-Ala-p-nitroanilide

Development of an agar diffusion method to measure elastase inhibition activity using Elastin-Congo red
Jung KH and Kim HJ
Journal of microbiology and biotechnology, 16(8), 1320-1324 (2006)
Faizan Abul Qais et al.
ACS omega, 6(29), 18823-18835 (2021-08-03)
Quorum sensing (QS) and biofilm inhibition are recognized as the novel drug targets for the broad-spectrum anti-infective strategy to combat the infections caused by drug-resistant bacterial pathogens. Many compounds from medicinal plants have been found to demonstrate anti-infective activity. However
Activation pattern of neutrophils from blood of elderly individuals with Candida-related denture stomatitis
Gasparoto TH, et al.
European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 31(6), 1271-1277 (2012)
Salivary immunity in elderly individuals presented with Candida-related denture stomatitis
Gasparoto T, et al.
Gerodontology, 29(2), e331-e339 (2012)
AiiM lactonase strongly reduces quorum sensing controlled virulence factors in clinical strains of Pseudomonas aeruginosa isolated from burned patients
Lopez-Jacome LE, et al.
Frontiers in Microbiology, 10, 2657-2657 (2019)
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Elastase Function and Importance

Elastase application index for understanding leukocyte elastase, a 29KDa serine endoprotease.

Elastase Function and Importance

Elastase application index for understanding leukocyte elastase, a 29KDa serine endoprotease.

Elastase Function and Importance

Elastase application index for understanding leukocyte elastase, a 29KDa serine endoprotease.

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