D3689

(S)-3,5-Dihydroxyphenylglycine hydrate

≥98% (HPLC), powder

• Synonyme(s) : S-DHPG
• Formule empirique (notation de Hill): C₈H₉NO₄ · xH₂O
• Numéro CAS: 162870-29-3
• Poids moléculaire : 183.16 (anhydrous basis)
• Numéro MDL: MFCD11044457
• Code UNSPSC : 12352209
• ID de substance PubChem : 24278366
• Nomenclature NACRES : NA.77

Propriétés

• Pureté: ≥98% (HPLC)
• Forme: powder
• Conditions de stockage: desiccated; protect from light
• Couleur: white
• Température de stockage: −20°C
• Chaîne SMILES: O.N[C@H](C(O)=O)c1cc(O)cc(O)c1
• InChI: 1S/C8H9NO4.H2O/c9-7(8(12)13)4-1-5(10)3-6(11)2-4;/h1-3,7,10-11H,9H2,(H,12,13);1H2/t7-;/m0./s1
• Clé InChI: QZEFIWWBQUKNFA-FJXQXJEOSA-N
• Informations sur le gène: human ... GRM1(2911)

Description

Application

(S)-3,5-Dihydroxyphenylglycine hydrate has been used:

• as mGluR1/5 agonist for metabotropic glutamate receptor 1 (mGluR1/5) activation in synaptoneurosomal preparations
• in ACSF for DHPG stimulation
• to inject into basolateral amygdala to study its effect on memory expression

Actions biochimiques/physiologiques

(S)-3,5-Dihydroxyphenylglycine hydrate is a group I metabotropic glutamate receptor agonist.

Caractéristiques et avantages

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This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Attention

air sensitive

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315,H319,H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves