C9275

Calcium Ionophore A23187 hemicalcium salt

powder

• Synonyme(s) : A23187 hemicalcium salt, Antibiotic A 23187 hemicalcium salt, Calcimycin hemicalcium salt, Calimycin hemicalcium salt
• Formule empirique (notation de Hill) : C₂₉H₃₆Ca_0.5N₃O₆
• Numéro CAS: 59450-89-4
• Poids moléculaire : 542.65
• UNSPSC Code: 12352200
• NACRES: NA.32
• PubChem Substance ID: 24893145
• MDL number: MFCD00077678
• Beilstein/REAXYS Number: 6765084

Propriétés

• sterility: non-sterile
• Quality Segment: 200
• form: powder
• color: yellow
• solubility: DMSO: soluble, ethanol: soluble
• antibiotic activity spectrum: Gram-positive bacteria, fungi
• mode of action: cell membrane | interferes
• storage temp.: 2-8°C
• SMILES string: CNc1ccc2oc(C[C@H]3O[C@@]4(CC[C@H]3C)O[C@@H]([C@H](C)C[C@H]4C)[C@H](C)C(=O)c5ccc[nH]5)nc2c1C(=O)O[Ca]OC(=O)c6c(NC)ccc7oc(C[C@H]8O[C@@]9(CC[C@H]8C)O[C@@H]([C@H](C)C[C@H]9C)[C@H](C)C(=O)c%10ccc[nH]%10)nc67
• InChI: 1S/2C29H37N3O6.Ca/c2*1-15-10-11-29(17(3)13-16(2)27(38-29)18(4)26(33)20-7-6-12-31-20)37-22(15)14-23-32-25-21(36-23)9-8-19(30-5)24(25)28(34)35;/h2*6-9,12,15-18,22,27,30-31H,10-11,13-14H2,1-5H3,(H,34,35);/q;;+2/p-2/t15-,16-,17-,18-,22-,27+,29?;15-,16-,17-,18-,22-,27+,29+;/m11./s1
• InChI key: LAQWEYASNNRUGY-PLYBNSMSSA-L

Description

Application

Ionophore highly selective for Ca²⁺. Potentiates responses to NMDA but not quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.

Ionophore highly selective for Ca²⁺. Stimulates nitric oxide production in cells by calmodulin-dependent constitutive nitric oxide synthase.

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves