C6512

Cholesteryl hemisuccinate

• Synonyme(s) : 3β-Hydroxy-5-cholestene 3-hemisuccinate, 5-Cholesten-3β-ol 3-hemisuccinate, Cholesteryl hydrogen succinate
• Formule empirique (notation de Hill) : C₃₁H₅₀O₄
• Numéro CAS: 1510-21-0
• Poids moléculaire : 486.73
• NACRES: NA.23
• PubChem Substance ID: 24892873
• UNSPSC Code: 12352103
• EC Number: 216-148-6
• MDL number: MFCD00037705

Propriétés

• form: liquid crystal
• Quality Segment: 200
• SMILES string: [H][C@@]([C@H](C)CCCC(C)C)([C@@]1(C)CC[C@@]23[H])CC[C@]1([C@](CC=C4C[C@H](CC[C@]34C)OC(CCC(O)=O)=O)2[H])[H]
• InChI: 1S/C31H50O4/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(35-29(34)14-13-28(32)33)15-17-30(22,4)27(24)16-18-31(25,26)5/h9,20-21,23-27H,6-8,10-19H2,1-5H3,(H,32,33)/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1
• InChI key: WLNARFZDISHUGS-MIXBDBMTSA-N

Description

General description

Cholesteryl hemisuccinate (CHEMS) is an acidic cholesterol ester. It self assembles into bilayers in alkaline and neutral aqueous media. CHEMS exhibits pH sensitive polymorphism. It consists of succinic acid esterified to the beta-hydroxyl group of cholesterol. This chemical modification results in the ability of CHEMS to adopt a lamellar assembly in suitable aqueous media, whereas cholesterol forms monohydrate crystals in an aqueous environment.

Application

• Experimental determination and computational interpretation of biophysical properties of lipid bilayers enriched by Cholesteryl Hemisuccinate: Provides insights into the effects of Cholesteryl Hemisuccinate on phospholipid bilayers, contributing to a deeper understanding of its biophysical properties (W Kulig et al., 2015).

Informations sur la sécurité

• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)